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KMID : 0358419940370112147
Korean Journal of Obstetrics and Gynecology
1994 Volume.37 No. 11 p.2147 ~ p.2153
Transcervical Chorionic Villus Sampling in 120 Cases
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Abstract
Cytogenetic data for chorionic villus sampling(CVS) are presented, which was performed from December 1990 till December 1992. In 97.5% of cases, successful cytogenetic diagnosis was obtained from cultural method, and no case was failed to obtain
cytogenetic data if sampling was done effectively.
Six cases (5%) for abnormal karyotype were noted. In those cases mosaicism and non-mosaicism were observed with equal frequency, but was confirmed as normal is following amniocentesis in all three cases of mosaic and non-mosaic tetraploidy.
This indicates that if there showed abnormality in ploidy in cultured CVS, it should be subjected to follow up by amniocentesis. The rate or maternal cell contamination was 3.32%.
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